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People with multiple sclerosis who experience this symptom more likely to have greater disability and spinal lesions

People with multiple sclerosis (MS) who experience restless leg syndrome are more likely to have greater disability and MRI lesions than those who do not, a new study has found.

The study’s participants filled out questionnaires such as the International Restless Legs Syndrome Study Group Rating Scale, which assesses severity, the Epworth Sleepiness Scale, which looks at the likelihood of sleepiness during the day, and the Pittsburgh Sleep Quality Index, which assesses sleep habits and quality over the past month.

A quarter of people with MS experienced restless leg syndrome, which was seven times higher than in the control group of people without MS.

People in the MS group were not more likely to have daytime sleepiness and poor life quality than the control group, but the scores for these factors were significantly higher in people with MS who had restless leg syndrome than those who didn’t, with 78% of the restless leg syndrome MSers experiencing impaired sleep compared with 21% of those with MS but not restless legs.

People with restless leg syndrome were also found to have higher scores in the Expanded Disability Status Scale, and more spinal lesions found from MRI scans.

Researchers also concluded that DMT choice didn’t have an impact on the severity of restless leg syndrome, sleep quality, or daytime sleepiness.

Source: MS-UK 04 May 2021

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