A prospective cohort study of 192 patients from the southern Alberta MS clinic registry explored why and in what circumstance people with MS may experience depression. The study’s researchers found that men are more likely to experience depression than women.
Participants completed baseline risk factor assessment questionnaires and a Patient Health Questionnaire every two weeks for six months to assess depressive symptoms in real time.
During those six months, 36 cases of depression were reported. The incidence of depression were 0.019 for women and higher in men at 0.044.
Fatigue, limited mobility, and poor self-esteem or resilience were found to be most associated with periods of serious depression among the study’s participants.
The researchers concluded that 'depression in MS exhibits a risk factor profile similar to that of depression in the general population, with the additional impact of MS illness-related factors.'
'Potentially modifiable risk factors, such as coping with stress and resiliency, present opportunities for focus of further research in depression in MS treatment and prevention efforts.'
This study, 'Determinants and incidence of depression in multiple sclerosis: A prospective cohort study,' was published in the Journal of Psychosomatic Research.
Source: MS-UK (21/07/17)