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Drug found to reduce bladder pressure in people with MS

Oral fesoterodine fumarate can reduce bladder pressure and improve quality of life in people with multiple sclerosis (MS)-related bladder impairments, a new study has shown.

During a three-month trial of the treatment, the results showed there were statistically significant improvements in lots of measures of bladder function. One was that it reduced the amount of force the destrusor urinae muscle put on the bladder.

The drug also increased the capacity of urine the bladder could hold, and improved quality of life.

Fesoterodine fumarate works by blocking the signals that tell the detrusor muscle to squeeze. It is used to treat an overactive bladder when the cause isn’t known, but so far there has been limited studies on how effective it is for people who have a neurogenic overactive bladder specifically.

Fesoterodine fumarate (8 mg) is an efficacious [treatment] in patients with [spinal cord damage] and MS, as it significantly decreases the detrusor pressure, increases the bladder capacity and compliance, and improves the quality of life,” the researchers concluded.

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